Working to Overcome Resistance, Relapse and Metastasis by Targeting Adaptive Stress and Immunosuppression

We believe that adaptive stress pathways and immunosuppressive tumor microenvironments are key mechanisms by which tumors achieve resistance to treatment and ultimately result in relapse and metastasis.

Despite the clinical improvements that have been made with the use of targeted therapies, cancer cells leverage adaptive stress and immunosuppressive pathways to adapt, survive, and become resistant to treatment.

We are leading the way in the development of innovative cancer therapy candidates that target adaptive stress responses and modulate innate and adaptive immunity.