Jonathan Lanfear, MBA

President and Chief Executive Officer, Jonathan Lanfear, is an accomplished biopharmaceutical executive with more than 25 years of experience in the life sciences industry and has demonstrated distinct success in creating and driving strategies, building and developing teams, establishing R&D partnerships, and creating new business opportunities. Prior to joining HiberCell, Jonathan was a Principal at Lanfear Advisors LLC, where he provided Corporate Strategy and Operations consultancy services to public and private sector biotech and bio/pharmaceutical companies.  Prior to establishing his consulting practice in 2020, he was the Global Head of R&D Business Development at Takeda Pharmaceuticals, based in Cambridge, MA.

Before joining Takeda in 2011, Jonathan spent approximately eight years at Pfizer Inc as a Senior Director and Transactions Lead in the Worldwide Business Development, Strategy, & Innovation (WWBDS&I) organization based in New York.  His prior roles also include Biotechnology Equity Research at AG Edwards/Wachovia and Team Leader, GMP Operations and Downstream Processing at Searle/Pharmacia (prior to the company’s acquisition by Pfizer).  Over his career, Jonathan has led hundreds of transactions of all types, integrated acquired entities, lead operations, and managed strategic alliances/partnerships.  He holds a Bachelor’s degree in Chemical Engineering and a Master’s degree in Bioengineering, both from the University of Michigan (Ann Arbor), along with an MBA from Washington University (St. Louis).  Jonathan is also a member of the Board of Directors of Molecular Templates, an oncology focused, publicly traded company based in New Jersey.

Nandita Bose, Ph.D.

Nandita Bose, Ph.D., has more than 18 years of accomplishment and innovation in the immuno-oncology field. She joined HiberCell from Biothera Pharmaceuticals, Inc., where she served as senior vice president of translational immunology. She has extensive experience in translational research involving delineation of immunopharmacodynamic effects in healthy volunteers and cancer patients as part of Phase I/II/III company-sponsored trials and investigator-initiated trials/ compassionate-use studies.

In addition to being adjunct faculty at North Dakota State University, she has held leadership roles in several scientific organizations. As the only industry member of the Education Committee of American Association of Immunologists (AAI), she has chaired committee-sponsored symposia to mentor undergrads and post-doctoral fellows. She is a working member of the Industry Council of Society for Immunotherapy of Cancer (SITC) and has sat on scientific grant review committees for the American Association for Cancer Research (AACR). She is a reviewer for several cancer immunology journals including SITC’s leading journal, Journal for Immunotherapy of Cancer (JITC).

Nandita earned her Ph.D. in biomedical sciences from the University of Georgia and conducted her postdoctoral work in cellular immunology at University of Minnesota and 3M Pharmaceuticals.

Michele Gargano, MS.c.

Michele Gargano, MS.c., has almost 30 years of industry experience in early-stage to BLA/NDA drug development. She brings extensive leadership experience having held positions of increasing responsibility throughout her career. Prior to joining HiberCell, Michele was the vice president of clinical development and program management at Biothera Pharmaceuticals, Inc., where she was responsible for managing clinical operations, cross-functional programming and regulatory affairs for multiple development programs. She has been responsible for 14 INDs for the treatment of cancer, various gastrointestinal, hepatic, and ophthalmic indications, and cystic fibrosis working closely with FDA’s CDER and CDRH divisions and select global health authorities. She has authored numerous clinical documents and regulatory submissions including clinical protocols, meeting briefing packages, breakthrough therapy and orphan drug applications, and has managed collaborative/ licensing relations furthering development.

Michele holds a B.A. in cultural anthropology and government from Sweet Briar College, and a general certificate and M.Sc. in social anthropology from the London School of Economics.

Eric Lightcap, Ph.D.

Eric Lightcap is a passionate and accomplished scientist with 24 years of experience in oncology and immuno-oncology drug discovery. As a leader managing biochemists, cell biologists, computational biologists and bioinformaticians, he has a successful history of applying mechanistic studies to highly novel therapies, leveraging insights from functional and correlative genomics and proteomics with in vitro, ex vivo and in vivo studies, to inform the translation of multiple oncology assets into the clinic. These efforts led to the exploration of diverse and unexpected biology. In particular, his exploration of the mechanism of action for Velcade resulted in an appreciation of the role of the integrated stress response, especially endoplasmic reticulum stress, in sensitive models.

He has worked on both small molecule and antibody teams and served on phase 1 clinical teams for the successful development and application of pharmacodynamic and predictive biomarkers, including for Velcade (clinical pathway engagement biomarker), pevonedistat (mechanism of action leading to the clinical exploration of carboplatin combination and validation of ERCC1 as a predictive biomarker of combination benefit), TAK-676 (clinical pathway engagement biomarker) and TAK-981 (characterization as an innate immune stimulator).

Eric received a B.S. in Biochemistry with Honors from Indiana University, Bloomington; a Ph.D. in Biochemistry from the University of Wisconsin-Madison; and completed a postdoctoral fellowship at Northwestern University, Evanston. Eric began his work in oncology at ProScript, a small biotech company where he first worked on Velcade and neddylation, and through acquisitions transitioned to LeukoSite, Millennium, and Takeda.

José Iglesias, M.D.

José Iglesias, M.D., is consultant chief medical officer at HiberCell. He has more than 30 years of experience in oncology. Prior to working with HiberCell, José was vice president and head of translational medicine at Boston Biomedical Inc., where he was responsible for the clinical development of seven early pipeline compounds in immuno-oncology, solid tumor oncology and hematologic malignancies.

Previously, José was chief medical officer at Biothera where he was responsible for the clinical development program of Imprime-PGG. Prior to that, he was the chief medical officer for Bionomics where he was responsible for the clinical development of its oncology pipeline, including antivascular agents, monoclonal antibodies and small molecule kinase inhibitors. Before that, he served as vice president, clinical development, at Celgene Corporation, where he was responsible for the Phase III development of Abraxane in pancreatic cancer, lung cancer and metastatic breast cancer.

José is author or co-author of more than 60 publications in the area of Oncology, with over 6,000 citations. He received his M.D. in oncology and cancer biology from the Universidad de Montevideo, Uruguay.

Philip Rowlands, Ph.D.

As our consulting Head of Development, Philip Rowlands brings deep experience developing new classes of transformative medicines and technology platforms with a goal of improving outcomes for patients fighting cancer.  Phil has spent 32 years in large and mid-size pharmaceutical companies in roles spanning preclinical and clinical R&D.  Trained as a pharmacologist, toxicologist and embryologist, his career started in 1988 in developmental toxicology, first at Zeneca/ICI, and then at Sterling Drug in the UK. Through a series of roles of increasing responsibility in preclinical development, based in the UK, Europe, and then the US, he worked at Sterling, Sanofi, GD Searle and Pharmacia. In 2003, following acquisition, he transferred to Pfizer as an exploratory development director and has been focused exclusively on oncology drug development from that time. At Pfizer, Phil led multiple programs spanning small molecule and biologic modalities, and crossing multiple mechanistic classes including anti-angiogenesis, signal transduction, cell cycle inhibition, and immunotherapy.  Programs he oversaw through different phases of preclinical and clinical development that ultimately led to new medicines included: bosutinib, crizotinib, dacomitinib, exemestane, inotuzumab, palbociclib, and tremelimumab.

In 2011, Phil moved to Takeda/Millennium, initially, as lead portfolio management and program leadership, and later, among a small management group piloting the first version of a fully integrated Therapeutic Area group comprising program leadership, program and portfolio management, and clinical development into one unit responsible for oncology R&D strategy, oversight of execution against that strategy, and development portfolio goals and budget. From 2015-2020, Phil was Oncology Therapeutic Area Head.  In this time, working closely with discovery and commercial partners, he oversaw the critical pivot of the research strategy to development of next generation breakthrough immune-oncology programs, the acquisition of ARIAD, new indication delivery for Adcetris, Ninlaro and Iclusig, new medicines in brigatinib and mobocertinib, regional approvals for cabozantinib and niraparib, and advancement into the clinic of the next wave of immunotherapy approaches including a novel STING agonist, a sumoylation inhibitor, an attenuated cytokine, an armored oncolytic vaccine, and critical partnerships to bring in multiple next generation cell therapy and bispecific platforms.  Consistently a champion of the central role of the multifunctional project team as the core of strategic development and execution, Phil also played a key part in generating and leading key initiatives to advance the integration of scientific, medical, commercial and patient inputs into strategic development and the practice of asset strategy.